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QUEST (Quadrivalent HPV Vaccine Evaluation Study) is a Canada-wide study designed to evaluate whether 2 doses of the HPV vaccine are just as effective as 3 doses at preventing Human Papillomavirus (HPV) infection and cervical cancer.

A 2 dose schedule of the HPV vaccine means (vs a 3 dose schedule):

• Fewer doses (shots) for girls
• A more affordable vaccine, which means:
• more women will be able to receive the vaccine
• Middle/low income countries are more likely to provide the vaccine to girls (since a 2 dose schedule is cheaper)
• Protecting more women against cervical cancer

Participation helps researchers:

• Understand how long protection lasts;
• Evaluate if there is a difference between girls who received 2 doses and those who received 3 doses of the HPV vaccine